Mfg Part Number
Ab00912-1.1
Vector Labs Ab00912-1.1 Anti-ectodysplasin A [EctoD2], Mouse IgG1, kappa (200 μg)
Quick Overview
This antibody was raised by immunising Eda-deficient Tabby mice with an active recombinant form of EDA1 (Fc-EDA1).
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | EctoD2 |
| Synonyms: | O54693; Q92838; Ectodysplasin-A; EDA |
| Amount: | 200 μg |
| Application Codes Clone: | block; SDS-PAGE; WB; FC; ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody recognises the conserved extracellular, receptor-binding region of murine, avian and human ectodysplasin-A. |
| Application Notes: | The specificity of this antibody for EDA has been confirmed in SDS-PAGE, Western blot, ELISA, native gel electrophoresis and FC experiments (Kowalczyk-Quintas et al, 2014). This antibody blocks mammalian and avian EDA1 and EDA2 from binding EDAR (Kowalczyk-Quintas et al, 2014). When administered to pregnant wild-type mice, this antibody induces foetal ectodermal dysplasia (Kowalczyk-Quintas et al, 2014). Therapeutically, this antibody may be useful in the treatment of disorders arising as a result of excessive EDA1 action. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |