Mfg Part Number
Ab00935-205.1
Vector Labs Ab00935-205.1 Anti-Parvovirus [MAbE], Dog IgM, kappa (50 μg)
Quick Overview
This antibody was raised by immunising rats with feline panleukopenia virus (FPV)-b.
$692.90
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| Product Class: | Purified |
|---|---|
| Clone ID: | MAbE |
| Synonyms: | canine parvovirus; CPV; feline panleukopenia virus; FPV |
| Amount: | 50 μg |
| Application Codes Clone: | IP; RIA; ELISA; neutralisation; EM |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2b |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric dog antibody was made using the variable domain sequences of the original Rat IgG2b format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | This antibody recognises both canine parvovirus (CPV-a and -b), feline panleukopenia virus (FPV-a and -b), binding to antigenic site B on the capsid. It also cross-reacts with mink enteritis virus. |
| Application Notes: | This antibody is able to neutralise FPV-a and -b and CPV- and -b in haemagglutination inhibition assays (Parrish & Carmichael, 1983). It has also been used in immunoprecipitation and RIA analysis (Parrish & Carmichael, 1983). A Fab derived from this antibody has also been shown, in ELISA experiments, to recognise CPV and FPV capsids (Nelson et al, 2007), and to potently neutralise CPV (Organtini et al, 2016). This Fab has also been used in cryo-electron microscopy to determine the structure of CPV (Organtini et al, 2016). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |