Mfg Part Number
Ab00951-2.0
Vector Labs Ab00951-2.0 Anti-gH [YC15], Mouse IgG2a, kappa (200 μg)
Quick Overview
Antibodies were produced from a murine hybridoma.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | YC15 |
| Synonyms: | KSHV gH; Glycoprotein H; Kaposi's sarcoma-associated herpesvirus glycoprotein H; KSHV glycoprotein H; KSHV envelope glycoprotein H; Envelope glycoprotein H |
| Amount: | 200 μg |
| Application Codes Clone: | FC; NTRL |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 21440007 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This mAb binds KSHV glycoprotein H. KSHV is a human herpesvirus which is associated with Kaposi's sarcoma, however is also implicated in 2 distinct B cell lymphoproliferative disorders. |
| Application Notes: | YC15 was reformatted as a scFv fragment and combined with Pseudomonas aeruginosa exotoxin A to create an immunotoxin against KSHV-infected cells (Cai & Berger, 2011). YC15 was shown to bind cells expressing gH on the surface using flow cytometry, where binding was sufficient to neutralise gH activity and also induce a cytotoxic effect. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |