Mfg Part Number
Ab00994-10.160
Vector Labs Ab00994-10.160 Anti-CD38 [MU551], Human IgG1-Fc Fusion, Fc Silent™, (100 μg)
Quick Overview
The C-terminal domain of human CD38 (residue 45–300) was expressed and produced in a yeast expression system. The purified recombinant protein was used as an antigen to immunize llamas. Phage display technology was used to obtain positive clones against CD38.
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| Product Class: | Purified |
|---|---|
| Clone ID: | MU551 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | Cluster of Differentiation 38; ADP-Ribosyl Cyclase 1; ADPRC1; ADPRC 1; 2-Phospho-Cyclic-ADP-Ribose Transferase; Cyclic ADP-Ribose Hydrolase 1; 2-Phospho-ADP-Ribosyl Cyclase; NAD(+) Nucleosidase; ADP-Ribose Transferase; Ecto-Nicotinamide Adenine Dinucleoti |
| Amount: | 100 μg |
| Application Codes Clone: | Crystallography |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | hcIgG |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Llama hcIgG format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | MU551 binds an epitope that is close to the middle of the CD38 molecule, on the opposite side of the active site pocket. The residues composing this epitope are: K69, Y70, E72, I73, H74, P75, R78, T136, Q137, V138, Q139, R140, D141, M142, F143, D147, Y152, V288, K289, N290, P291, E292. |
| Application Notes: | The nanobody MU551 has been crystallised with CD38. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |