Mfg Part Number
Ab01017-1.69
Vector Labs Ab01017-1.69 Anti-PD-1H [mam82], Mouse Bispecific, anti-mPD-L1, Bispecific antibody, kappa (50 μg)
Quick Overview
The antibody was generated by immunising a PD-1H-KO mouse with mouse PD-1H Ig fusion protein and adjuvant.
$692.90
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| Product Class: | Purified |
|---|---|
| Clone ID: | mam82 |
| Heavy Chain Modification: | Bispecific antibody |
| Synonyms: | VISTA; VISR; B7-H5; B7H5; GI24; PP2135; SISP1; DD1alpha; C10orf54; chromosome 10 open reading frame 54; V-set immunoregulatory receptor |
| Amount: | 50 μg |
| Application Codes Clone: | ELISA; IHC; block |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This is a bispecific anti-mouse antibody created by fusing anti-PDL-1 VHH domains to the C-terminus of the heavy chains) of the anti-mouse PD-1H (VISTA) antibody clone mam82 in a mouse IgG1 D265 format. The mouse IgG1 D265 a format is an Fc-silenced forma |
| Specificity Statement: | This antibody specifically binds PD-1H. |
| Application Notes: | This antibody has been characterised by ELISA and by staining of PD-1H-transfected P815 mastocytoma. No background staining of WT or PD-1H-KO T cells was observed. This antibody inhibits WT OT-II T cell proliferation at high OVA peptide concentrations (Flies D et al, 2014). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |