Mfg Part Number
Ab01019-10.3
Vector Labs Ab01019-10.3 Anti-CD7 [YTH3.2.6], Human IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
The k-secreting myeloma line Y3/Ag1.2.3 was fused with spleen cells from DA rats immunised with normal human lymphocytes.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | YTH3.2.6 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | GP40; LEU-9; TP41; Tp40; T-cell leukemia antigen; P41 protein; YTH3.2.6AG5 |
| Amount: | 200 μg |
| Application Codes Clone: | IF; FC; ELISA; IHC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2b |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Rat IgG2b format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds CD7. |
| Application Notes: | The fraction of human lymphocyte cells recognised by YTH 3.2 was analysed by flow cytometry, using fluorescein-labelled F(ab')2 fragments of rabbit anti-(rat Ig) to stain the antibody. Binding has also been characterised by ELISA. In preliminary tests, graft rejection in patients with steroid-resistant kidney rejection indicated that graft rejection could be reversed by YTH 3.2 injections (Hale et al, 1985). This antibody has been used to stain T-cell dependent areas in immunohistology (King et al, 1989). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |