Mfg Part Number
Ab01041-23.0
Vector Labs Ab01041-23.0 Anti-CD103 [YDBYT 280.2], Rabbit IgG, kappa (200 μg)
Quick Overview
The original version of this antibody was raised against murine CD103.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | YDBYT 280.2 |
| Synonyms: | Integrin alpha-E; Integrin alpha M290 |
| Amount: | 200 μg |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2b |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2b format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody recognizes murine CD103 (Integrin alpha-E). Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. Mice expressing a null mutation of the alpha-E subunit gene exhibit a marked reduction in the numbers of intraepithelial lymphocytes in the gut and in the development of gut-associated lymphoid aggregates, supporting a specific role for this integrin in mediating retention of lymphocytes in the intestinal wall (Uniprot). |
| Application Notes: | This antibody is recommended for the detection of murine CD103 ((Integrin alpha-E). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |