Mfg Part Number
Ab01044-10.0
Vector Labs Ab01044-10.0 Anti-CD30 [YMSM636], Human IgG1, kappa (200 μg)
Quick Overview
This antibody was raised by immunising rats with a mouse CD30 - human IgG1 fusion protein.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | YMSM636 |
| Synonyms: | TNFRSF8; YMSM 636.4.10; YMSM636; Tumor necrosis factor receptor superfamily member 8; CD30L receptor; Lymphocyte activation antigen CD30; Tnfrsf8 |
| Amount: | 200 μg |
| Application Codes Clone: | FC; ELISA; activating |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2b |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Rat IgG2b format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody recognises CD30 which is a receptor for TNFSF8/CD30L. It is thought to regulate cellular growth and lymphocytes development as well as gene expression via NF-kappa-B. |
| Application Notes: | This antibody can be used to initiate apoptosis in isolated human peripheral blood eosinophils and thus it might be researched as a potential agent for therapeutic agents for hypereosinophilic diseases useful in the treatment of allergic diseases, respiratory diseases, skin diseases, autoimmune diseases, immunodeficiency diseases, digestive diseases, neoplastic diseases and parasitic infections (US20040156847A1). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |