Mfg Part Number
Ab01052-7.1
Vector Labs Ab01052-7.1 Anti-4-1BB [LOB12.3], Rat IgG2a, kappa (200 μg)
Quick Overview
This antibody was generated by immunizing rats with recombinant CD137-Fc fusion protein.
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| Product Class: | Purified |
|---|---|
| Clone ID: | LOB12.3 |
| Synonyms: | CD137; TNFRSF9; 41BB; 4-1BBL Ligand; Tumor necrosis factor superfamily member 9; TNF receptor superfamily member 9; LOB 12.3; LOB123; LOB12.3 |
| Amount: | 200 μg |
| Application Codes Clone: | FC; activate |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This reformatted rat antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds to mouse 4-1BB (CD137). |
| Application Notes: | This antibody can be used to detect mouse 4-1BB (CD137). In its original rat IgG1 format, this antibody had agonistic effect and prolonged survival of mice bearing CT26 or A31 tumors. In the original publication another clone LOB12 disclosed which has a rat IgG2a isotype. This has led to some confusion in the literature with regards to the original isotype of LOB12 and LOB12.3. We offer this antibody in both formats as well as murine versions so that researchers may choose the isotype most appropriate for their assays. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |