Mfg Part Number
Ab01070-205.0
Vector Labs Ab01070-205.0 Anti-OspA [LA-2], , kappa (50 μg)
Quick Overview
This antibody was generated by immunising mice.
$692.90
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| Product Class: | Purified |
|---|---|
| Clone ID: | LA-2 |
| Synonyms: | Outer surface protein A |
| Amount: | 50 μg |
| Application Codes Clone: | IF; WB; IP; NTRL |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 11183781 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2b |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric dog antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | Recognises the three surface-exposed loops of the C-terminal domain of OspA that are on the tip of the elongated molecule most distant from the lipid-modified N-terminus. The residues involved in these loops are: 203-220, 224-233, and 246-257. |
| Application Notes: | LA-2 binds to Borrelia Burgdorferi, the causative agent of Lyme disease (Borreliosis) has been used in serological analyses of B. burgdorferi isolates by immuno-blotting and immunofluorescence (Kramer et al, 1990). This antibody has also been applied to affinity purification of OspA. This antibody neutralised B. burgdorferi infectivity when passively transferred to SCID mice (Schaible et al, 1990). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |