Mfg Part Number
Ab01104-15.0

Vector Labs Ab01104-15.0 Anti-influenza [3-10B], Human IgM, lambda (50 μg)

Quick Overview
This human antibody to influenza nucleoprotein (NP) 2-8C was obtained from human subjects in compliance with good clinical practice guidelines and the Declaration of Helsinki.
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Product Class:Purified
Clone ID:3-10B
Synonyms:Influenza NP; Influenza B Nuclear Protein; Influenza Nuclear Protein
Amount:50 μg
Application Codes Clone:neutralisation assays
Shipping Temperature:Wet Ice
Buffer Composition:PBS with 0.02% Proclin 300.
Original Format:IgG1
Storage Temperature:Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:This reformatted human antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:This antibody reacts with influenza B virus nucleoprotein (NP). Influenza A and B are the two types of influenza viruses that cause epidemic human disease. Influenza B viruses currently circulating are divided into two antigenically and genetically distinct groups: the Victoria and Yamagata lineages. Influenza virus B is a genus in the virus family Orthomyxoviridae. A limited host range means that Influenza virus B pandemics are rare. The nucleoprotein protects the negative strand viral RNA from nucleases by encapsidating it. Encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.
Application Notes:This antibody binds to formalin fixed cells so is very useful for development of neutralisation assays. (NB: This work is yet to be published. The information is obtained via personal communication with the originator).
More Information
Brand Vector Labs
UNSPSC 12161500