Mfg Part Number
Ab01141-10.0
Vector Labs Ab01141-10.0 Anti-P-selectin [PL7-6], Human IgG1, kappa (200 μg)
Quick Overview
This antibody was raised by immunising BALB/c mice with washed platelets.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | PL7-6 |
| Synonyms: | GMP-140; SELP; CD62 antigen-like family member P; Granule membrane protein 140; Leukocyte-endothelial cell adhesion molecule 3; LECAM3; Platelet activation dependent granule-external membrane protein; PADGEM; CD62P |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; WB; FC |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 7520038 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for human P-selectin, which is expressed by activated platelets. |
| Application Notes: | This antibody has been used in flow cytometric detection of thrombin-stimulated platelets (Katayama et al, 1992), and a chimeric mouse/human version of this antibody also preferentially reacts with activated platelets (Kurome et al, 1994). This could enable the detection of platelets aggregating at sites of blood vessel injury, or the delivery of clot-dissolving drugs. The specificity of this antibody for CD62 has been confirmed in western blot and ELISA (Katayama et al, 1992), and ELISA analysis based on this antibody has been used to assess P-selectin levels in plasma sample of patients post-angina (Ikeda et al, 1995). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |