Mfg Part Number
Ab01145-1.1
Vector Labs Ab01145-1.1 Anti-Streptococcus pneumoniae capsular polysaccharide serotype 6B [Hyp6BM8], Mouse IgG1, kappa (200 μg)
Quick Overview
This antibody was raised by immunising BALB/c mice with S. pneumoniae 6B capsular polysaccharide conjugated to keyhole limpet hemocyanin.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | Hyp6BM8 |
| Synonyms: | CPS 6B; capsular PS 6B |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; FC |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 12055241 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgM |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgM format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This S. pneumoniae serogroup 6-specific antibody binds to serogroup 6B capsular polysaccharide with an affinity of 2.44 x 10^11 M^-1.This antibody also cross-reacts with the 6A polysaccharide, with an affinity of 6.41 x 10^10 M^-1, and also reacts with serotypes 6C and 6D. |
| Application Notes: | This antibody has been used in flow cytometric analysis as part of a panel of serogroup 6-specific mAbs to define the serologic properties of new S. pneumoniae isolates (Oliver et al, 2013). The ability of this antibody to bind S. pneumoniae 6B and 6A serotypes has been characterised in ELISA analysis (Sun et al, 2001). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |