Mfg Part Number
Ab01154-6.1

Vector Labs Ab01154-6.1 Anti-Murine leukemia virus p30 gag capsid polypeptide [R187], Rat IgG1, kappa (200 μg)

Quick Overview
This antibody was raised by immunising Mendell-Osbourne rats with spleen focus-forming virus (SFFV)-infected nonproducer normal at kidney cells. SFFV is a replication-defective murine leukemia virus.
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Product Class:Purified
Clone ID:R187
Synonyms:MLV p30; Murine Leukemia Virus Capsid Protein
Amount:200 μg
Application Codes Clone:IF; IP
Shipping Temperature:Wet Ice
Origin Pub PMID:10697114
Buffer Composition:PBS with 0.02% Proclin 300.
Original Format:IgG1
Storage Temperature:Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Specificity Statement:This antibody recognises the murine leukemia virus (MuLV) p30gag capsid polypeptide. It also binds to the MuLV Pr65gag precursor polyprotein. It reacts with Friend murine leukemia helper virus (F-MuLV).
Application Notes:The binding specificity of this antibody for the murine leukemia virus (MuLV) p30gag capsid polypeptide has been confirmed in immunoprecipitation and immunofluorescence analysis (Cheseboro et al, 1983). When cell surface binding to virus-infected cells was investigated through immunoprecipitation, this antibody was observed to react with all ecotropic and amphotropic strains tested, but not SFFV (Cheseboro et al, 1983). When expressed intracellularly, an scFv with the same binding specificity as this antibody inhibits the production of MuLV (Marin et al, 2000).
More Information
Brand Vector Labs
UNSPSC 12161500