Mfg Part Number
Ab01157-1.1
Vector Labs Ab01157-1.1 Anti-paclitaxel [3A3], Mouse IgG1, kappa (200 μg)
Quick Overview
This antibody was raised by immunising BALB/c mice with a solution of 7-xylosyltaxol conjugated to the carrier protein bovine serum albumin (XylTax–BSA).7-xylosyltaxol is a taxol (paclitaxel) derivative, which binds to tubulin and inhibits microtubule dis
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| Product Class: | Purified |
|---|---|
| Clone ID: | 3A3 |
| Synonyms: | PT; PTX; Taxol; 7-Xylosylpaclitaxel; Taxol-7-xyloside; 7-xylosyltaxol |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 26940321 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for paclitaxel, an anti-neoplastic agent derived from the Pacific yew. It displays low cross-reactivity with other naturally-occurring taxanes. |
| Application Notes: | This antibody has been used in an indirect competitive enzyme-linked immunosorbent assay to determine the paclitaxel content of yew tree samples, with a detection range of 0.098–312.5 μg ml−1 (Chao et al, 2012). An scFv derived from this antibody reacts with both free and immobilised paclitaxel in icELISA analysis, and exhibits less cross-reactivity for paclitaxel-related compounds (Yusakul et al, 2016). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |