Mfg Part Number
Ab01171-15.0
Vector Labs Ab01171-15.0 Anti-N9 Neuraminidase [NC41 ], Human IgM, kappa (50 μg)
Quick Overview
This antibody was raised by immunising BALB/c mice with pronase-released heads of N9 neuraminidase.
$692.90
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| Product Class: | Purified |
|---|---|
| Clone ID: | NC41 |
| Synonyms: | N9-N |
| Amount: | 50 μg |
| Application Codes Clone: | crystallisation |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for the neuraminidase antigen of subtype N9, which also possesses HA activity. It cross-reacts with both avian and whale influenza. NC41 epitope is dominated by a few high-energy interactions. |
| Application Notes: | A Fab fragment derived from this antibody by papain digestion has been used in X-ray diffusion analysis to crystallise N9 neuraminidase from avian influenza virus (Laver et al, 1987;Tulip et al, 1992) and whale avial-like virus (Tulip et al, 1992). In neuraminidase inhibition assays, this antibody has been shown to suppress the yield of virus from infected cells (Colman et al, 1987) |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |