Mfg Part Number
Ab01184-21.0
Vector Labs Ab01184-21.0 Anti-N-acetyl-ganglioside (GM2) [E1], Mouse IgM, kappa (50 μg)
Quick Overview
The antibody was generated by injecting BALB/c mice with GM2 ganglioside incorporated into liposomes.
$692.90
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | E1 |
| Amount: | 50 μg |
| Application Codes Clone: | ELISA; IHC |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 17306373 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgM |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | Gangliosides are glycosphingolipids expressed on the cell surface membranes of most mammalian cell types. In ELISA experiments E1 showed a highly-restricted binding specificity, detecting only GM2 (not GM1 or GM3). The antibody recognises only the N-acetylneuraminic acid deratives of gangliosides; no N-glycolylneuraminic acid derivatives were recognised. |
| Application Notes: | ELISA demonstrated E1 has a highly-restricted binding specificity, binding only to GM2. IHC studies showed positivity with E1 in primary lung carcinomas, but no reactivity with corresponding normal tissues (Alfonso et al, 1995). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |