Mfg Part Number
Ab01188-1.1
Vector Labs Ab01188-1.1 Anti-Cyclosporin A [R454511], Mouse IgG1, kappa (100 μg)
Quick Overview
BALB/c mice were immunised with a D-Lys^8-Cs derivative coupled to a carrier protein.
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| Product Class: | Purified |
|---|---|
| Clone ID: | R454511 |
| Synonyms: | CsA; ciclosporin A, cyclosporine A |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; crystallography |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 1566062 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | R454511 binds to residues 1, 2, 3, 4, 5, 9 and 11 of CsA. |
| Application Notes: | Mutagenesis of Cs-derivatives identified that R454511 binds to residues 1, 2, 3, 4, 5, 9 and 11 of CsA (Quesniaux et al, 1990). In ELISA experimenets, R454511 was found to bind to Cs conjugated with both Thr^2 (Thr^2-Cs-BSA) and Lys^8 (D-Lys^8-Cs-BSA) (Quesniaux et al, 1990). The crystal structure of R454511 in complex with CsA has been obtained to 2.65 Å resolution (Altschuh et al, 1992). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |