Mfg Part Number
Ab01211-23.0
Vector Labs Ab01211-23.0 Anti-Erythropoietin receptor [Ab198], Rabbit IgG, kappa (200 μg)
Quick Overview
Ab198 was generated by immunising XenoMouse mice (humanised immune system) with soluble human EpoR.
$517.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | Ab198 |
| Synonyms: | EPO-R |
| Amount: | 200 μg |
| Application Codes Clone: | RIA; SPR; SFA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG2 format, for improved compatibility with existing reagents, assays and techniques. |
| Application Notes: | RIA showed that Ab198 competes with EPO for binding to EPO-R. SPR determined the Kd of Ab198 binding to EPO-R as 13.9 nM. In an EPO dependent human cell proliferation assay Ab198 stimulated proliferation of the F36E cell line. Ab198 also induced proliferation of human erythroid producing cells derived from progenitor cells in a dose-dependent manner. In a cynomolgus bone marrow CFUe assay Ab198 induced the formation of CFU-E colonies. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |