Mfg Part Number
Ab01230-23.0
Vector Labs Ab01230-23.0 Anti-RAGE [2A11], Rabbit IgG, kappa (200 μg)
Quick Overview
Human RAGE protein.
$517.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | 2A11 |
| Synonyms: | AGER; advanced glycosylation end product-specific receptor; receptor for advanced glycosylation end products |
| Amount: | 200 μg |
| Application Codes Clone: | Western blot; IHC; IF; ELISA; FC; SPR |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | 2A11 is specific for the V-domain of human advanced glycosylation end product-specific receptor. It recognises both the glycosylated and non-glycosylated forms. |
| Application Notes: | ELISA confirmed the specificity of 2A11 for the V-domain of RAGE, with a binding affinity (Kd) of 7.6 nM. ELISA was also used to confirm that the binding of 2A11 to RAGE is glycosylation independent. In SPR experiments the Kd of 2A11 binding to RAGE was determined as 0.38 nM. Flow cytometry and immunochemistry were used to visualise the binding of 2A11 to HEK-RAGE cells. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |