Mfg Part Number
Ab01238-10.9
Vector Labs Ab01238-10.9 Anti-Receptor tyrosine-protein kinase erbB-3 [BCD090-M2], Human IgG1-Fc fusion, (200 μg)
Quick Overview
The sdAb was selected from a Llama-derived phage antibody library.
$517.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | BCD090-M2 |
| Synonyms: | HER3; Proto-oncogene-like protein c-ErbB-3; tyrosine kinase-type cell surface receptor HER3; erbB3 |
| Amount: | 200 μg |
| Application Codes Clone: | SPR; crystallography |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | VHH |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using a variable domain sequence of the original VHH format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | BCD090-M2 recognises erbB3, a receptor tyrosine kinase. The overexpression of erbB3 in breast cancers is associated with reduced survival in patients. |
| Application Notes: | The crystal structure of BCD090-M2 has been obtained (Eliseev et al, 2018). SPR indicates the equilibrium dissociation constant for BCD090-M2 bound to immobilised erbB3 is 1 μm (Eliseev et al, 2018). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |