Mfg Part Number
Ab01267-2.3
Vector Labs Ab01267-2.3 Anti-IL-27p28 [MM27-7B1], Mouse IgG2a, Fc Silent™, kappa (200 μg)
Quick Overview
This antibody was raised by immunising mice with a p28–EBI3 fusion protein linked to ovalbumin polymers covered with glutaraldehyde (OVAglu).
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | MM27-7B1 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | MM27.7B1; MM27 7B1; MM277B1; Interleukin-27 subunit alpha; IL-27 subunit alpha; IL-27-A; IL27-A; p28; Il27; Il27a |
| Amount: | 200 μg |
| Application Codes Clone: | FC; blocking; ELISA; therapeutic |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody is specific for the IL-27 p28 subunit. |
| Application Notes: | This antibody has been used to detect intracellular IL-27 in flow cytometric analysis (Bosmann et al, 2014), and to detect serum and cell culture supernatant IL-27 in sandwich ELISA analysis (Marillier et al, 2014). This antibody blocks IL-27, and is able to restore IL‐9 and IL‐17A production in the presence of IL‐27 (Uyttenhove et al, 2011). Administration of this antibody blocks graft-versus-host disease upon B6 cell transfer to B6D2 recipient mice (Marillier et al, 2014). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |