Mfg Part Number
Ab01269-23.0

Vector Labs Ab01269-23.0 Anti-Macaque pan-species IgG [1B3], Rabbit IgG, kappa (200 μg)

Quick Overview
This antibody was raised by immunising mice with baboon IgG and screening hybridomas against IgG of different primate species.
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Product Class:Purified
Clone ID:1B3
Synonyms:Macaque IgG; Macaque immunoglobulin G
Amount:200 μg
Application Codes Clone:FC; ELISA
Shipping Temperature:Wet Ice
Buffer Composition:PBS with 0.02% Proclin 300.
Original Format:IgG1
Storage Temperature:Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:This antibody reacts with rhesus macaque IgG1 and IgG3, as well a cynomolgus monkey, pigtailed macaque and baboon IgG. It has minimal reactivity with human, mangabey, vervet, chimpanzee, or marmoset IgG.
Application Notes:This anti-macaque antibody has been used in ELISA analysis to detect rhesus anti-mouse antibodies in serum samples (Page et al, 2012). As this antibody is able to distinguish between human and macaque IgG, it has also been used in ELISA analysis to detect macaque antibodies raised against intravenously-administered human HIV broadly neutralising antibodies (Rosenberg et al, 2015). Additionally, it has been used in flow cytometric analysis to confirm the clearance of intravenously-administered anti-CD4 depleting antibody from the plasma of rhesus macaques (Mudd et al, 2011).
More Information
Brand Vector Labs
UNSPSC 12161500