Mfg Part Number
Ab01280-10.3
Vector Labs Ab01280-10.3 Anti-hINSR [IR 83-16], Human IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
This antibody was raised by immunising BALB/c mice with IM-9 lymphocytes, and boosting with purified human placental insulin receptor prior to fusion.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | IR 83-16 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | CD220; human insulin receptor; insulin receptor; HHF5; IR; 83 16 |
| Amount: | 200 μg |
| Application Codes Clone: | IP; stimulatory |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody reacts with human INSR, recognising an epitope on the alpha subunit (amino acids 191-290). It does not cross-react with rat insulin receptors, and does cross-react with rabbit, bovine, porcine and ovine receptors. |
| Application Notes: | This antibody has been used in immunoprecipitation assays, with radiolabelled human insulin receptor (hINSR) and hINSR-radiolabelled insulin complexes (Soos et al, 1986). This antibody has been shown to enhance insulin binding to IM-9 cells (Soos et al, 1986). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |