Mfg Part Number
Ab01280-23.0

Vector Labs Ab01280-23.0 Anti-hINSR [IR 83-16], Rabbit IgG, kappa (200 μg)

Quick Overview
This antibody was raised by immunising BALB/c mice with IM-9 lymphocytes, and boosting with purified human placental insulin receptor prior to fusion.
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Product Class:Purified
Clone ID:IR 83-16
Synonyms:CD220; human insulin receptor; insulin receptor; HHF5; IR; 83 16
Amount:200 μg
Application Codes Clone:IP; stimulatory
Shipping Temperature:Wet Ice
Buffer Composition:PBS with 0.02% Proclin 300.
Original Format:IgG1
Storage Temperature:Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:This antibody reacts with human INSR, recognising an epitope on the alpha subunit (amino acids 191-290). It does not cross-react with rat insulin receptors, and does cross-react with rabbit, bovine, porcine and ovine receptors.
Application Notes:This antibody has been used in immunoprecipitation assays, with radiolabelled human insulin receptor (hINSR) and hINSR-radiolabelled insulin complexes (Soos et al, 1986). This antibody has been shown to enhance insulin binding to IM-9 cells (Soos et al, 1986).
More Information
Brand Vector Labs
UNSPSC 12161500