Mfg Part Number
Ab01297-7.1
Vector Labs Ab01297-7.1 Anti-CD96 [6A6], Rat IgG2a, lambda (200 μg)
Quick Overview
This antibody was raised by immunising rats with murine CD96.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | 6A6 |
| Synonyms: | TACTILE; T-cell surface protein tactile; T cell-activated increased late expression protein |
| Amount: | 200 μg |
| Application Codes Clone: | blocking; FC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody is specific for murine CD96, and recognises an epitope in the first Ig domain. |
| Application Notes: | This antibody blocks murine CD96-CD155 interaction, and has been shown to bind to the first Ig domain of CD96 and compete with CD155 binding (Roman Aguilera et al, 2018). This antibody displays significant anti-metastatic activity in four experimental lung metastases models and one spontaneous tumour metastasis model (Roman Aguilera et al, 2018), with a potency greater than the anti-CD96 monoclonal antibodies 3.3 and 8B10. The binding specificity of this antibody has been determined in flow cytometric analysis of HEK-293 cells transfected with a range of CD96 Ig domain chimeric constructs (Roman Aguilera et al, 2018). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |