Mfg Part Number
Ab01300-1.1

Vector Labs Ab01300-1.1 Anti-FANCM [CV5.1], Mouse IgG1, kappa (200 μg)

Quick Overview
CV5.1 antibody was raised in mouse using His-tagged denatured FANCM (aa 1507-1679) made in E coli as the immunogen.
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Product Class:Purified
Clone ID:CV5.1
Synonyms:Fanconi Anemia M; Fanconi anemia group M protein; Fanconi anemia, complementation group M; Fanconi Anemia Complementation Group M; KIAA1596; Fanconi Anemia-Associated Polypeptide Of 250 Kda; ATP-Dependent RNA Helicase FANCM; Protein Hef Ortholog; FAAP250; Protein FANCM
Amount:200 μg
Application Codes Clone:WB; IF; ICC; IHC
Shipping Temperature:Wet Ice
Buffer Composition:PBS with 0.02% Proclin 300.
Original Format:IgG1
Storage Temperature:Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Specificity Statement:This antibody recognises human FANCM (other species were not tested but there is high sequence conservation). FANCM is a part of a larger FA (Fanconi anemia) complex. It is engaged in DNA repair, resistance to DNA cross-linking drugs and prevention of chromosomal breakage.
Application Notes:IHC: CV5.1 antibody successfully detected FANCM in human fetal and adult ovaries (Fouquet et al., 2017). WB: Fouquet et al. (2017) also performed western blot analysis detecting FANCM with this antibody. IHC: FANCM in human testicular sections was visualised by the CV5.1 antibody (Kasak et al., 2018).
More Information
Brand Vector Labs
UNSPSC 12161500