Mfg Part Number
Ab01300-1.6-BS
Vector Labs Ab01300-1.6-BS Anti-FANCM [CV5.1], Mouse Fab fragment, His-Tagged, kappa (1 mg)
Quick Overview
CV5.1 antibody was raised in mouse using His-tagged denatured FANCM (aa 1507-1679) made in E coli as the immunogen.
$5,162.30
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| Product Class: | Purified |
|---|---|
| Clone ID: | CV5.1 |
| Heavy Chain Modification: | His-Tagged |
| Synonyms: | Fanconi Anemia M; Fanconi anemia group M protein; Fanconi anemia, complementation group M; Fanconi Anemia Complementation Group M; KIAA1596; Fanconi Anemia-Associated Polypeptide Of 250 Kda; ATP-Dependent RNA Helicase FANCM; Protein Hef Ortholog; FAAP250; Protein FANCM |
| Amount: | 1 mg |
| Application Codes Clone: | WB; IF; ICC; IHC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS only. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody recognises human FANCM (other species were not tested but there is high sequence conservation). FANCM is a part of a larger FA (Fanconi anemia) complex. It is engaged in DNA repair, resistance to DNA cross-linking drugs and prevention of chromosomal breakage. |
| Application Notes: | IHC: CV5.1 antibody successfully detected FANCM in human fetal and adult ovaries (Fouquet et al., 2017). WB: Fouquet et al. (2017) also performed western blot analysis detecting FANCM with this antibody. IHC: FANCM in human testicular sections was visualised by the CV5.1 antibody (Kasak et al., 2018). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |