Mfg Part Number
Ab01314-1.1
Vector Labs Ab01314-1.1 Anti-vWF [F8/86], Mouse IgG1, kappa (200 μg)
Quick Overview
This antibody was raised against von Willebrand factor isolated from human plasma.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | F8/86 |
| Synonyms: | von Willebrand factor; von Willebrand antigen 2; von Willebrand antigen II; coagulation factor VIII VWF; factor VIII-related antigen; F8; F8VWF; VWD |
| Amount: | 200 μg |
| Application Codes Clone: | IHC; WB; ICC; FACS |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody recognises human von Willebrand factor (also know as Factor VIII related antigen). It is produced by endothelial cells and megakaryocytes and is involved in the process of hemostasis by engaging in adhesion of platelets to the sites of vascular injury. Mutations in this gene lead to Von Willebrand's disease which causes frequent bleeding. |
| Application Notes: | IHC: F8/86 antibody was used in immunohistochemistry expermients to stain against vWF in samples of murine stomach tissue in a study exploring the potential use of mesenchymal cells in myocardium regeneration (Freemen et al., 2015). ICC: This antibody was also used in an attempt to characterise human gingival microvascular endothelial cells where it identified vWF via immunocytochemical staining (DeCarlo et al., 2008). FACS: Another group has successfully used F8/86 antibody in a cell sorting procedure in a study which analysed the influence of physical environment on the rat mesenchymal stem cells (Xue et al., 2017). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |