Vector Labs Ab01314-10.6-BS Anti-vWF [F8/86], Human Fab fragment, His-Tagged, kappa (1 mg) Centrifuge Bundle Savings at Sycamore Life Sciences

Description

Product Class: Purified
Clone ID: F8/86
Heavy Chain Modification: His-Tagged
Synonyms: von Willebrand factor; von Willebrand antigen 2; von Willebrand antigen II; coagulation factor VIII VWF; factor VIII-related antigen; F8; F8VWF; VWD
Amount: 1 mg
Application Codes Clone: IHC; WB; ICC; FACS
Shipping Temperature: Wet Ice
Buffer Composition: PBS only.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody recognises human von Willebrand factor (also know as Factor VIII related antigen). It is produced by endothelial cells and megakaryocytes and is involved in the process of hemostasis by engaging in adhesion of platelets to the sites of vascular injury. Mutations in this gene lead to Von Willebrand's disease which causes frequent bleeding.
Application Notes: IHC: F8/86 antibody was used in immunohistochemistry expermients to stain against vWF in samples of murine stomach tissue in a study exploring the potential use of mesenchymal cells in myocardium regeneration (Freemen et al., 2015). ICC: This antibody was also used in an attempt to characterise human gingival microvascular endothelial cells where it identified vWF via immunocytochemical staining (DeCarlo et al., 2008). FACS: Another group has successfully used F8/86 antibody in a cell sorting procedure in a study which analysed the influence of physical environment on the rat mesenchymal stem cells (Xue et al., 2017).

Product Class:	Purified
Clone ID:	F8/86
Heavy Chain Modification:	His-Tagged
Synonyms:	von Willebrand factor; von Willebrand antigen 2; von Willebrand antigen II; coagulation factor VIII VWF; factor VIII-related antigen; F8; F8VWF; VWD
Amount:	1 mg
Application Codes Clone:	IHC; WB; ICC; FACS
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS only.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	This antibody recognises human von Willebrand factor (also know as Factor VIII related antigen). It is produced by endothelial cells and megakaryocytes and is involved in the process of hemostasis by engaging in adhesion of platelets to the sites of vascular injury. Mutations in this gene lead to Von Willebrand's disease which causes frequent bleeding.
Application Notes:	IHC: F8/86 antibody was used in immunohistochemistry expermients to stain against vWF in samples of murine stomach tissue in a study exploring the potential use of mesenchymal cells in myocardium regeneration (Freemen et al., 2015). ICC: This antibody was also used in an attempt to characterise human gingival microvascular endothelial cells where it identified vWF via immunocytochemical staining (DeCarlo et al., 2008). FACS: Another group has successfully used F8/86 antibody in a cell sorting procedure in a study which analysed the influence of physical environment on the rat mesenchymal stem cells (Xue et al., 2017).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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