Mfg Part Number
Ab01329-2.0
Vector Labs Ab01329-2.0 Anti-MUC1 [E29], Mouse IgG2a, lambda (200 μg)
Quick Overview
This antibody was raised by immunising Balb/c mice with EMA prepared from human milk fat globule.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | E29 |
| Synonyms: | MUC-1; Mucin-1; EMA; Breast carcinoma-associated antigen DF3; Cancer antigen 15-3; CA 15-3; Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary mucin; PUM; Polymorphic epithelial mucin; PEM; Tumor-associated epithelial membrane antigen; Tumor-associated mucin; CD227 |
| Amount: | 200 μg |
| Application Codes Clone: | IHC; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody recognises human EMA which belongs to a familiy of human milk fat globule (HMFG) proteins. It is present in milk as well as in various types of normal and neoplastic epithelia. |
| Application Notes: | E29 antibody has been widely used in studies on various types of neoplastic conditions and is recommended for immunohistochemistry alone or with other antibodies for formalin-fixed, paraffin-embedded tissue characterisation. For instance, Tajima and Koda (2015) used it as a part of immunohistochemical characterisation of the ectomesenchymal chondromyxoid tumor of the tongue. Another group immunohistochemically stained formalin-fixed pancreatic tumour tissue with E29 in order to label EMA (MUC1) (Woei-A-Jin et al., 2016). EMA is frequently positive in meningioma, which can be useful when distinguishing it from other intracranial neoplasms, e.g. Schwannomas. Finally, the absence of EMA staining may also be used as an important factor in tissue characterisation and cancer diagnosis. Lack of EMA signal is typical for certain tumours, such as adrenal carcinoma, seminomas, paraganglioma and hepatoma. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |