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Mfg Part Number

Ab01331-8.1

Vector Labs Ab01331-8.1 Anti-CD79a [HM57], Rat IgG2b, kappa (200 μg)

VECTOR LABS

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Quick Overview

This antibody was raised by immunising BALB/c mice with a synthetic peptide G-T-Y-Q-D-V-G-S-L-N-I-A-D-V-Q, representing amino acids 202-216 of the human mb-1 protein and conjugated to thyroglobulin.

$517.40

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Description

Product Class: Purified
Clone ID: HM57
Synonyms: MB-1; B-cell antigen receptor complex-associated protein alpha chain; Ig-alpha; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; Surface IgM-associated protein; MB-1 membrane glycoprotein
Amount: 200 μg
Application Codes Clone: IHC; IF; IP
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody recognises CD79a which is involved in initiation of the signal transduction cascade activated by binding of antigen to the B-cell receptor. CD79a is used as an adjunct to CD20 for detecting normal and neoplastic B cells in tissue sections.
Application Notes: CD79a is strongly expressed in various B-cell-derived conditions and thus this antibody is useful during identification and investigation of such diseases (via IF, IHC) (Mason et al., 1991). One group utilised it for immunofluorescent labelling of CD79a containing cells in bone marrow samples of pre-B lymphocyte acute leukemia patients (Mason et al., 1991). HM57 antibody can also be used for IP as it was very efficient in immunoprecipitating CD79a from NP-40 cells lysates (Mason et al., 1995). Finally, this antibody has been widely applied in veterinary research and proved successfull in recognising CD79a in various species, from chicken to dog (Doring et al., 2018).

Product Class:	Purified
Clone ID:	HM57
Synonyms:	MB-1; B-cell antigen receptor complex-associated protein alpha chain; Ig-alpha; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; Surface IgM-associated protein; MB-1 membrane glycoprotein
Amount:	200 μg
Application Codes Clone:	IHC; IF; IP
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	This antibody recognises CD79a which is involved in initiation of the signal transduction cascade activated by binding of antigen to the B-cell receptor. CD79a is used as an adjunct to CD20 for detecting normal and neoplastic B cells in tissue sections.
Application Notes:	CD79a is strongly expressed in various B-cell-derived conditions and thus this antibody is useful during identification and investigation of such diseases (via IF, IHC) (Mason et al., 1991). One group utilised it for immunofluorescent labelling of CD79a containing cells in bone marrow samples of pre-B lymphocyte acute leukemia patients (Mason et al., 1991). HM57 antibody can also be used for IP as it was very efficient in immunoprecipitating CD79a from NP-40 cells lysates (Mason et al., 1995). Finally, this antibody has been widely applied in veterinary research and proved successfull in recognising CD79a in various species, from chicken to dog (Doring et al., 2018).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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