Vector Labs Ab01332-13.12 Anti-CD79a [JCB117], Human IgG4-S228P, kappa (200 μg) Centrifuge Bundle Savings at Sycamore Life Sciences

Description

Product Class: Purified
Clone ID: JCB117
Synonyms: MB-1; B-cell antigen receptor complex-associated protein alpha chain; Ig-alpha; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; Surface IgM-associated protein; MB-1 membrane glycoprotein
Amount: 200 μg
Application Codes Clone: IHC; IF; WB
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody recognises CD79a which is involved in initiation of the signal transduction cascade activated by binding of antigen to the B-cell receptor. CD79a is used as an adjunct to CD20 for detecting normal and neoplastic B cells in tissue sections.
Application Notes: This antibody reacts very well with B-cells during immunohistochemical labelling of paraffin-embedded tissue samples. It detected most B-cell neoplasms tagging B-cells at various stages of maturation (Mason et al., 1995). Consequently, it may be used as a reliable marker in the detection and investigation of different B-cell conditions. For instance, it labels precursor B-cell acute lymphoblastic leukemia samples what makes it the most efficient marker of this disorder in paraffin-embedded tissue (Mason et al., 1995). Furthermore, this antibody may be useful in staining and identification of plasma cell myeloma and acute promyelocytic leukemia. For example, JCB117 antibody was utilised in the characterisation of multiple myeloma and it showed very strong immunostaining of the neoplastic cells (Requena et al., 2003).

Product Class:	Purified
Clone ID:	JCB117
Synonyms:	MB-1; B-cell antigen receptor complex-associated protein alpha chain; Ig-alpha; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; Surface IgM-associated protein; MB-1 membrane glycoprotein
Amount:	200 μg
Application Codes Clone:	IHC; IF; WB
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	This antibody recognises CD79a which is involved in initiation of the signal transduction cascade activated by binding of antigen to the B-cell receptor. CD79a is used as an adjunct to CD20 for detecting normal and neoplastic B cells in tissue sections.
Application Notes:	This antibody reacts very well with B-cells during immunohistochemical labelling of paraffin-embedded tissue samples. It detected most B-cell neoplasms tagging B-cells at various stages of maturation (Mason et al., 1995). Consequently, it may be used as a reliable marker in the detection and investigation of different B-cell conditions. For instance, it labels precursor B-cell acute lymphoblastic leukemia samples what makes it the most efficient marker of this disorder in paraffin-embedded tissue (Mason et al., 1995). Furthermore, this antibody may be useful in staining and identification of plasma cell myeloma and acute promyelocytic leukemia. For example, JCB117 antibody was utilised in the characterisation of multiple myeloma and it showed very strong immunostaining of the neoplastic cells (Requena et al., 2003).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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