Mfg Part Number
Ab01333-23.0
Vector Labs Ab01333-23.0 Anti-CD79b [B29/123], Rabbit IgG, lambda (200 μg)
Quick Overview
This antibody was raised against the sequence G-E-V-K-W-S-V-G-E-H-P-G-Q-E, representing the carboxy-terminus, from amino acid 215 on, of the human and murine B29 polypeptides.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | B29/123 |
| Synonyms: | B-cell antigen receptor complex-associated protein beta chain; B-cell-specific glycoprotein B29; Ig-beta; Immunoglobulin-associated B29 protein; B29; IGBAGM6; B29 123 |
| Amount: | 200 μg |
| Application Codes Clone: | IHC; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2b |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody recognises intracellular C-terminus of human and murine CD79b which is part of the B-cell antigen receptor which constitutes a disulphide linked heterodimer, consisting of CD79a (mb1) and CD79b / B29 polypeptides which are non-covalently associated with membrane bound immunoglobulins on B-cells. |
| Application Notes: | This antibody is recommended for the immunohistochemical and Western blot investigation of B-cells and their cancers which express CD79b. B29/123 antibody recognises specifically CD79b protein whose expression pattern during B-cell development is distinct from CD79a. Consequently, this antibody might be utilised in the investigation of processes associated with characteristic CD79b expression. For instance, one group used it in the immunofluorescence staining of WEHI231 cells transduced with LAPTM5-IRES-GFP in a study on B-cell activation (Ouchida et al., 2010). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |