Mfg Part Number
Ab01339-1.1
Vector Labs Ab01339-1.1 Anti-CD21L [R4/23], Mouse IgG1, kappa (200 μg)
Quick Overview
This antibody was raised by immunising BALB/c mice with C3 receptor-coated erythrocytes.
$517.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | R4/23 |
| Synonyms: | Complement receptor type 2; CR2; Complement C3d receptor; Epstein-Barr virus receptor; EBV receptor; CD21 |
| Amount: | 200 μg |
| Application Codes Clone: | IHC; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgM |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgM format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody recognises CD21L which is a long isoform of CD21 (CR2) (with an additional exon 10a). It is strongly expressed on dendritic reticulum cells and serves as a receptor for the complement elements (and is also bound by EBV). |
| Application Notes: | CD21L is strongly expressed in reticulum dendritic cells and R4/23 might be used for the identification of these cells. For instance, Schriever et al. (1989) used this antibody (among others) in an attempt to differentiate follicular dendritic cells from lymphoid dendritic cells. This antibody can be also utilised in the characterisation of certain cancers; for example, one group used it in an immunohistochemical analysis of frozen samples of tumour cells from diffuse large B‐cell lymphoma (Ogawa et al., 2004). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |