Mfg Part Number
Ab01340-10.0
Vector Labs Ab01340-10.0 Anti-CD9 [P1/33/2], Human IgG1, kappa (200 μg)
Quick Overview
This antibody was raised by immunising mice with acute lymphoblastic leukaemia cells.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | P1/33/2 |
| Synonyms: | CD9 antigen; 5H9 antigen; Cell growth-inhibiting gene 2 protein; Leukocyte antigen MIC3; Motility-related protein; MRP-1; Tetraspanin-29; Tspan-29; p24; BTCC-1; DRAP-27 |
| Amount: | 200 μg |
| Application Codes Clone: | IHC; FC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody recognises CD9 which is a glycoprotein with four transmembrane domains that is expressed on the surface of various blood cells, such as B lymphocytes, platelets, monocytes and others, and also on neurons and glia on the periphery. It is implicated in different functions, for example cell-cell adhesion, signal transduction and platelet activation. |
| Application Notes: | Antibodies against CD9 might be used in characterisation of acute leukaemias, other tumours and for functional studies on platelets. For instance, one group used P1/33/2 during immunohistochemical characterisation of frozen sections of melanoma ABCG2+IGR37 cells xenografts (Taghizadeh et al., 2010). Another group used this antibody (along with other anti-CD9 antibodies) to analyse CD9 expression level and distribution in different breast cancer cells (MDA, MA-11, and MCF-7) and they showed that CD9 might be a useful marker of the neoplastic cells as its expression was higher in cancer cells than in normal breast cells as well as it was additionally present in the nuclei of the malignant tissue (Rappa et al., 2014). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |