Mfg Part Number
Ab01341-10.3
Vector Labs Ab01341-10.3 Anti-CD10 [SS2/36], Human IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
This antibody was raised by immunising mice with common acute lymphoblastic leukaemia cells.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | SS2/36 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | Neprilysin; Atriopeptidase; Common acute lymphocytic leukemia antigen; CALLA; Enkephalinase; Neutral endopeptidase 24.11; NEP; Neutral endopeptidase; Skin fibroblast elastase; SFE; EC 3.4.24; EC 3.4.24.11 |
| Amount: | 200 μg |
| Application Codes Clone: | IHC; FC; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody recognises neprilysin which is a cell surface enzyme degrading various peptides, such as enkephalins, angiotensins and atrial natriuretic factor. |
| Application Notes: | Anti-Neprilysin antibodies have been used in the characterisation and identification of certain cancers and other conditions. For instance, CD10 (Neprilysin) is an important cell surface marker of human acute lymphocytic leukemia (ALL) and Daskalopoulou and colleagues (2001) used this antibody (along with others) during cytological diagnosis and subclassification of malignant lymphomas as a marker of ALL. SS2/36 antibody was also used for flow cytometric phenotyping of hairy cell leukemia cases (Jasionowski et al., 2003). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |