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Mfg Part Number

Ab01342-10.3

Vector Labs Ab01342-10.3 Anti-CD16 [DJ130c], Human IgG1, Fc Silent™, kappa (200 μg)

VECTOR LABS

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Quick Overview

This antibody was raised by immunising mice with CD16 antigen.

$517.40

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Description

Product Class: Purified
Clone ID: DJ130c
Heavy Chain Modification: Fc Silent™
Synonyms: CD16; Low affinity immunoglobulin gamma Fc region receptor III; Low affinity immunoglobulin gamma Fc region receptor III-A; Low affinity immunoglobulin gamma Fc region receptor III-B; CD16; CD16a; CD16b; FCGR3; FCGR3A; FCGR3B; Fc-gamma RIII-alpha; Fc-gamma RIII; Fc-gamma RIIIa; FcRIII; FcRIIIa; FcR-10; IgG Fc receptor III-2; Fc-gamma RIII-beta; Fc-gamma RIIIb; FcRIIIb
Amount: 200 μg
Application Codes Clone: IHC; IP; FC; WB
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody recognises an epitope in the first membrane-distal domain of both CD16a and CD16b. CD16 is a low affinity receptor for IgG, and plays an important role in mediating ADCC by NK cells.
Application Notes: DJ130c may be used in identification and characterisation of various cancers. For instance, one group utilised this antibody in the analysis of expression profiles of gastric cancer xenografts exposed to cisplatin and considerable alteration in the expression level of CD16 was observed (Cai et al., 2017). Another group used this antibody to identify and compare different subpopulations of macrophages and their potential relation to acute heart transplant rejection, both via immunofluorescence and immunohistochemistry in tissue samples (van den Bosch et al., 2017).

Product Class:	Purified
Clone ID:	DJ130c
Heavy Chain Modification:	Fc Silent™
Synonyms:	CD16; Low affinity immunoglobulin gamma Fc region receptor III; Low affinity immunoglobulin gamma Fc region receptor III-A; Low affinity immunoglobulin gamma Fc region receptor III-B; CD16; CD16a; CD16b; FCGR3; FCGR3A; FCGR3B; Fc-gamma RIII-alpha; Fc-gamma RIII; Fc-gamma RIIIa; FcRIII; FcRIIIa; FcR-10; IgG Fc receptor III-2; Fc-gamma RIII-beta; Fc-gamma RIIIb; FcRIIIb
Amount:	200 μg
Application Codes Clone:	IHC; IP; FC; WB
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	This antibody recognises an epitope in the first membrane-distal domain of both CD16a and CD16b. CD16 is a low affinity receptor for IgG, and plays an important role in mediating ADCC by NK cells.
Application Notes:	DJ130c may be used in identification and characterisation of various cancers. For instance, one group utilised this antibody in the analysis of expression profiles of gastric cancer xenografts exposed to cisplatin and considerable alteration in the expression level of CD16 was observed (Cai et al., 2017). Another group used this antibody to identify and compare different subpopulations of macrophages and their potential relation to acute heart transplant rejection, both via immunofluorescence and immunohistochemistry in tissue samples (van den Bosch et al., 2017).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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