Mfg Part Number
Ab01343-1.1
Vector Labs Ab01343-1.1 Anti-CD3e [PC3/188A], Mouse IgG1, kappa (200 μg)
Quick Overview
This antibody was raised by immunising mice with a peptide sequence (156-168) from the intracytoplasmic portion of the epsilon-chain of CD3.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | PC3/188A |
| Synonyms: | Leu4/T3; T-cell surface glycoprotein CD3 epsilon chain; -cell surface antigen T3/Leu-4 epsilon chain; CD3e; CD3 epsilon; CD3e antigen; TCRE |
| Amount: | 200 μg |
| Application Codes Clone: | IHC; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody recognises CD3 epsilon which is a part of the TCR-CD3 complex present on all mature T-lymphocyte cells and is crucial in the adaptive immunity. |
| Application Notes: | This anti-CD3 has been used for the identification of normal and malignant T lymphocytes in paraffin embedded or frozen tissue sections. For instance, one group labelled paraffin-embedded pancreatic sections with PC3/188A antibody to identify T-lymphocytes while investigating the role of the oligodeoxynucleotide IMT504 on diabetes in rats (Bianchi et al., 2012). Another group also used this antibody to identify T lymphocytes by staining rat brain tissue samples against CD3 in a study investigating the mechanisms of neuroinflammation (Doursout et al., 2013). Finally, Roballo and Bushman (2019) utilised PC3/188A antibody as a marker of T cells during immunohistochemical analysis of frozen sciatic nerve sections. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |