Mfg Part Number
Ab01381-10.3
Vector Labs Ab01381-10.3 Anti-LRP Light Chain [8B8], Human IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
This antibody was raised by immunising mice with human LRP, purified by affinity chromatography from detergent placenta extracts.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | 8B8 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | low density lipoprotein receptor-related protein; LRP-85; LRP1; alpha-2-macroglobulin receptor; A2MR; APR; apolipoprotein E receptor; APOER; cluster of differentiation 91; CD91; LRP-1; 85 kDa light chain of LRP |
| Amount: | 200 μg |
| Application Codes Clone: | IB; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for LRP1, and reacts with an epitope in the 85kDa light beta chain (LRP-85 subunit). |
| Application Notes: | The specificity of this antibody has been confirmed in immunoblotting experiments (Strickland et al, 1990). This antibody has been used in Western blot analysis of HEK-293 cells transfected with human full-length LRP1 fused to EGFP, to confirm fusion protein expression (Laatsch et al, 2012). Additionally, this antibody has been used in Western blot analysis to measure LRP1 protein expression levels, both in human vascular smooth muscle cells (Costales et al, 2015; Sendra et al, 2008) and human monocyte-derived macrophages (Llorente-Cortés et al, 2007). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |