Mfg Part Number
Ab01413-10.0
Vector Labs Ab01413-10.0 Anti-haloperidol [Clone A], Human IgG1, kappa (200 μg)
Quick Overview
This antibody was raised against a haloperidol-BSA conjugate in which the drug was linked to the protein carrier via a succinic acid linker arm through the tertiary alcohol function on the piperidine ring (succinic acid conjugate).
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| Product Class: | Purified |
|---|---|
| Clone ID: | Clone A |
| Synonyms: | Haldol; 185(2)-1; A; Einalon S; Eukystol; Aloperidin; Bioperidolo; Brotopon; Dozic; Duraperidol; Halosten; Keselan; Linton; Peluces; Serenace; Sigaperidol |
| Amount: | 200 μg |
| Application Codes Clone: | RIA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | Thi antibody recognises haloperidol which is one of the major antipsychotic drugs. It is a D2 dopamine receptor antagonist and is widely used in treatment of schizophrenia, psychosis and mania. Antibody A prefers a folded confirmation of haloperidol and binds to a different site on the molecule than anti-haloperidol antibody D. |
| Application Notes: | RIA: radioligand binding assays were performed to asses binding affinity of the anti-haloperidol A antibody (Kd=3.3 nM). (Sherman et al., 1986). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |