Mfg Part Number
Ab01467-13.12
Vector Labs Ab01467-13.12 Anti-CD3 zeta [G3], Human IgG4-S228P, kappa (200 μg)
Quick Overview
This antibody was raised by immunising BALB/c mice with a 113 amino acid synthetic peptide corresponding to the cytoplasmic domain of murine CD3 zeta.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | G3 |
| Synonyms: | TCR zeta; CD3z; TCRz; CD247; T-cell surface glycoprotein CD3 zeta chain; T-cell receptor T3 zeta chain; CD3-zeta; TCR-zeta |
| Amount: | 200 μg |
| Application Codes Clone: | WB; IP; ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2c |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2c format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody recognises COOH-terminal region of CD3 zeta which is a part of the TCR-CD3 complex present on all mature T-lymphocyte cells and is crucial in the adaptive immunity. |
| Application Notes: | G3 antibody might be utilised in the detection and analysis of T cells as well as in research on lymphoid malignancies. This antibody was shown to exhibit strong affinity to CD3 zeta in ELISA and Western blot and to be very effective in precipitating CD3 zeta (as well as its phosphorylated form) from Jurkat T cell lysate (van Oers et al., 1994). It is also used |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |