Mfg Part Number
Ab01481-10.6-BS

Vector Labs Ab01481-10.6-BS Anti-CD133 [CD133-scFv-1], Human Fab fragment, His-Tagged, kappa (1 mg)

Quick Overview
This antibody fragment was selected against recombinant CD133 via phage display from the Tomlinson I and J libraries.
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Product Class:Purified
Clone ID:CD133-scFv-1
Heavy Chain Modification:His-Tagged
Synonyms:Prominin-1; AC133; Prominin-like protein 1
Amount:1 mg
Application Codes Clone:FC; ELISA; WB
Shipping Temperature:Wet Ice
Buffer Composition:PBS only.
Original Format:scFv
Storage Temperature:Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:This reformatted human antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:This antibody recognises CD133 which is thought to be engaged in cell differentiation, proliferation and apoptosis.
Application Notes:CD133 is used as a cancer stem cell (CSCs) marker in a variety of carcinomas. High affinity of the CD133-scFv-1, which detects CD133, was confirmed via competitive ELISA agianst a commercailly available antibody directed against the same epitope (Xia et al., 2013). Immunoblot and flow cytometry were performed to demonstrate the specificity of the CD133-scFv-1 antibody in PLC/PRF/5 cells (Xia et al., 2013).
More Information
Brand Vector Labs
UNSPSC 12161500