Mfg Part Number
Ab01486-13.12
Vector Labs Ab01486-13.12 Anti-CD22 [LL2 (EPB2)], Human IgG4-S228P, kappa (200 μg)
Quick Overview
This antibody was raised by immunising Balb/c mice with Raji cells or a fragmented cell mixture.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | LL2 (EPB2) |
| Synonyms: | Leu14; B-cell receptor CD22; B-lymphocyte cell adhesion molecule; BL-CAM; Sialic acid-binding Ig-like lectin 2; Siglec-2; T-cell surface antigen Leu-14; EPB2; EPB-2 |
| Amount: | 200 μg |
| Application Codes Clone: | RIA; FC; IHC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody recognises CD22, which is a cytoplasmic molecule expressed in progenitor and early-pre B cells. |
| Application Notes: | This antibody has been used in research on the diagnosis and treatment of non-Hodgkin's B cell lymphoma. Specificity to B-cell line of the LL2 (EPB-2) antibody was confirmed by radioimmunobinding and flow cytometry, where it did not bind to any other targets, such as T cells and normal diploid cells at the same time labelling malignant lymphoma tissue (Pawlak-Byczkowska et al., 1989). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |