Mfg Part Number
Ab01489-2.0-VXM

Vector Labs Ab01489-2.0-VXM Anti-CD19 [6D5], Mouse IgG2a, kappa (5 mg)

Quick Overview
This antibody was raised by immunising rats with mouse CD19-expressing K562 human erythroleukemia cells.
$1,189.50
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Product Class:VivopureX
Clone ID:6D5
Synonyms:Leu12; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Differentiation antigen CD19 T-cell surface antigen Leu-12; CD19; B4
Amount:5 mg
Application Codes Clone:FC; IHC; IP; WB
Shipping Temperature:Wet Ice
Buffer Composition:PBS only.
Original Format:IgG2a
Storage Temperature:All VivopureX products are formulated in PBS only without addition of preservatives. To ensure optimal storage and prevent microbial contamination, only open and dispense under sterile conditions. Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:This antibody recognises mouse CD19, which is a transmembrane glycoprotein that regulates B lymphocyte development, activation, and differentiation. This clone 6D5 recognizes the same epitope as the published clone 1D3.
Application Notes:6D5 antibody has been extensively used to identify B cells in various experimental arrangements. It can be efficiently utilised in the localisation of B cells in various tissues. For instance, one group stained murine spleen tissue cryosections to visualise lymphomas in azathioprine-treated mice (Chalastanis et al., 2010). This antibody has also been widely used in flow cytometry. One group utilised in the flow cytometric identification of B cells in a study investigating the relation of microglia depletion and MPTP neurotoxicity (Yang et al., 2018).
More Information
Brand Vector Labs
UNSPSC 12161500