Mfg Part Number
Ab01491-7.1
Vector Labs Ab01491-7.1 Anti-CD115/M-CSFR [AFS98], Rat IgG2a, kappa (200 μg)
Quick Overview
This antibody was raised against CD115.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | AFS98 |
| Synonyms: | CSF-1R; Macrophage colony-stimulating factor 1 receptor; Csf1r; CD115; CSF-1 receptor; EC 2.7.10.1; CSF-1-R; M-CSF-R; Proto-oncogene c-Fms |
| Amount: | 200 μg |
| Application Codes Clone: | FC; blocking; WB; IHC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody recognises mouse M-CSFR (CD115, CSF-1R) which is a membrane protein that influences tissue macrophage and osteoclast differentiation and proliferation. |
| Application Notes: | AFS98 has been widely used in various flow cytometric analyses to label CD115 antigen. For instance, one group used it to detect monocytes in a mouse blood sample (Buschor et al., 2019). Similarly, Huo and colleagues (2017) utilised this antibody to identify monocytes in mouse blood in order to assess whether myelopoiesis was not a cause of the increase in the monocytes number. This antibody has been also successfully used to deplete macrophages (Ho et al., 2016). Finally, it was also utilised in the immunofluorescence staining of tissue sections prepared from 4% paraformaldehyde-fixed and decalcified bones (Dong et al., 2016). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |