Mfg Part Number
Ab01495-10.3
Vector Labs Ab01495-10.3 Anti-ribosomal P protein [B10], Human IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
This antibody was derived from BALB/c mice immunised with TcP2b.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | B10 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | 60S acidic ribosomal protein P2-B; P2B; R13; P2b; TcP2b; R13 |
| Amount: | 200 μg |
| Application Codes Clone: | functional assays |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody recognises DDxGF sequence of the C-terminal of eukaryotic ribosomal P proteins. |
| Application Notes: | Both B10 mAb and scFv were demonstrated to detect eukaryote ribosomal P proteins with a high specificity demonstrated by the alanine-scanning mutagenesis of peptide R13 (López Bergami et al., 2003). Consequently, this antibody can be used in the detection of ribosomal P proteins in various eukarote tissues. Finally, anti-P protein antibodies are observed in certain pathologies, such as Trypanosoma cruzi infection and SLE, and thus B10 antibody might be utilised as a model for the investigation of the immunology of these diseases (López Bergami et al., 2003). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |