Mfg Part Number
Ab01502-10.3
Vector Labs Ab01502-10.3 Anti-CD45RA [OTH-74D4], Human IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
This antibody was raised by immunising mice with an EBV-transformed B cell line from a patient with MHC class II deficiency.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | OTH-74D4 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | PTPRC; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; L-CA; T200; CD45; LY5; T200 glycoprotein; T200 leukocyte common antigen; CD45RA isoform; OTH 74D4 |
| Amount: | 200 μg |
| Application Codes Clone: | FC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | OTH-74D4 antibody recognises CD45RA, which is an CD45 isoform containing only protein A region.The CD45RA antigen is expressed mostly on naïve CD4+, CD8+ and gd+ T and on most B and NK lymphocytes. Generally the CD45RA antigen density decreases upon activation. |
| Application Notes: | OTH-74D4 antibody is recommended for the flow cytometric identification of CD45RA. The CD45RA expression on immune cells is used as one of the key surface antigen to determine the functional status and also to define the end-stage of human T cells. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |