Mfg Part Number
Ab01531-10.3
Vector Labs Ab01531-10.3 Anti-SIRP alpha [SAF10.1], Human IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
This antibody was raised by immunisisng BALB/c mice with an eukaryotically expressed SIRPα-Fc fusion protein consisting of the extracellular domain and emulsified with complete Freund’s adjuvant and followed by two subsequent boosts of SIRPα-Fc fusion protein emulsified with IFA (Lee et al., 2007).
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| Product Class: | Purified |
|---|---|
| Clone ID: | SAF10.1 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | Tyrosine-protein phosphatase non-receptor type substrate 1; SHP substrate 1; SHPS-1; Brain Ig-like molecule with tyrosine-based activation motifs; Bit; CD172 antigen-like family member A; Inhibitory receptor SHPS-1; Macrophage fusion receptor; MyD-1 antigen; Signal-regulatory protein alpha-1; Sirp-alpha-1; Signal-regulatory protein alpha-2; Sirp-alpha-2; Signal-regulatory protein alpha-3; Sirp-alpha-3; p84; CD172a |
| Amount: | 200 μg |
| Application Codes Clone: | WB; IF; IP; FC; binding assay |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody recognises an epitope in the membrane most distal domain (D1) of SIRP alpha. It crossreacts with other SIRPs. |
| Application Notes: | SAF10.1, can be used to detect SIRPs in a wide variety of tissues and cell types. For instance, this antibody was successfully used to detect SIRPs from COS7.2 cell lysates via Western blot (Lee et al., 2008). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |