Mfg Part Number
Ab01547-23.0
Vector Labs Ab01547-23.0 Anti-CD81 [1.3.3.22], Rabbit IgG, kappa (200 μg)
Quick Overview
This antibody was raised by immunizing mice with a B-Cell line derived from a Burkitt lymphoma.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | 1.3.3.22 |
| Synonyms: | TSPAN-28; Tetraspanin-28; TSPAN28; CD81 antigen; 26 kDa cell surface protein TAPA-1; Target of the antiproliferative antibody 1; TAPA-1; TAPA1 |
| Amount: | 200 μg |
| Application Codes Clone: | WB; FC; IHC; IF; FACS |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | 1.3.3.22 antibody recognizes CD81. Human CD81 is a member of the tetraspanin family of leukocyte cell surface molecules which are involved in signal transduction, cell-cell adhesion and cellular activation. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. It is present on a wide variety of leukocytes. |
| Application Notes: | Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas and thus 1.3.3.22 can be used as a research antibody in the studies on lymphoma therapeutics. This antibody is also recommended in the detection and analysis of CD81 via various methods. For instance, 1.3.3.22 antibody was used in the identification of CD81 in human arteries by immunohistochemistry (Rohlena et al., 2009). 1.3.3.22 was also successfully utilized during flow cytometric detection of CD81 on KM3 cells (Higginbottom et al., 2000). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |